diff --git a/erpnext/regional/italy/e-invoice.xml b/erpnext/regional/italy/e-invoice.xml
index 7c436a2b449..ef1e94ff27b 100644
--- a/erpnext/regional/italy/e-invoice.xml
+++ b/erpnext/regional/italy/e-invoice.xml
@@ -18,25 +18,27 @@
 <Nazione>{{ address.country_code }}</Nazione>
 {%- endmacro %}
 
-{%- macro render_discount_or_margin(item) -%}
-{%- if (item.discount_percentage and item.discount_percentage > 0.0) or item.margin_type %}
+{%- macro render_discount_or_margin(item, tax_divisor) -%}
+{%- if item.discount_percentage and item.discount_percentage > 0.0 %}
 <ScontoMaggiorazione>
-  {%- if item.discount_percentage > 0.0 %}
   <Tipo>SC</Tipo>
   <Percentuale>{{ format_float(item.discount_percentage) }}</Percentuale>
-  {%- endif %}
-  {%- if item.margin_rate_or_amount > 0.0 -%}
-    <Tipo>MG</Tipo>
-    {%- if item.margin_type == "Percentage" -%}
-      <Percentuale>{{ format_float(item.margin_rate_or_amount) }}</Percentuale>
-    {%- elif item.margin_type == "Amount" -%}
-      <Importo>{{ format_float(item.margin_rate_or_amount) }}</Importo>
-    {%- endif -%}
-  {%- endif %}
 </ScontoMaggiorazione>
-{%- endif -%}
+{%- endif %}
+{%- if item.margin_rate_or_amount and item.margin_rate_or_amount > 0.0 %}
+<ScontoMaggiorazione>
+  <Tipo>MG</Tipo>
+  {%- if item.margin_type == "Percentage" -%}
+    <Percentuale>{{ format_float(item.margin_rate_or_amount) }}</Percentuale>
+  {%- elif item.margin_type == "Amount" -%}
+    <Importo>{{ format_float(item.margin_rate_or_amount / tax_divisor) }}</Importo>
+  {%- endif -%}
+</ScontoMaggiorazione>
+{%- endif %}
 {%- endmacro -%}
 
+{%- set has_inclusive_tax = doc.taxes | selectattr("included_in_print_rate") | list | length > 0 -%}
+
 <?xml version='1.0' encoding='UTF-8'?>
 <p:FatturaElettronica xmlns:ds="http://www.w3.org/2000/09/xmldsig#"
   xmlns:p="http://ivaservizi.agenziaentrate.gov.it/docs/xsd/fatture/v1.2"
@@ -179,6 +181,7 @@
     </DatiGenerali>
     <DatiBeniServizi>
       {%- for item in doc.e_invoice_items %}
+      {%- set tax_divisor = (1 + item.tax_rate / 100) if has_inclusive_tax and item.tax_rate else 1 %}
       <DettaglioLinee>
         <NumeroLinea>{{ item.idx }}</NumeroLinea>
         <CodiceArticolo>
@@ -188,8 +191,9 @@
         <Descrizione>{{ html2text(item.description or '') or item.item_name }}</Descrizione>
         <Quantita>{{ format_float(item.qty) }}</Quantita>
         <UnitaMisura>{{ item.stock_uom }}</UnitaMisura>
-        <PrezzoUnitario>{{ format_float(item.net_rate or item.price_list_rate or item.rate, item_meta.get_field("rate").precision) }}</PrezzoUnitario>
-        {{ render_discount_or_margin(item) }}
+        {%- set item_unit_net_price = (item.price_list_rate / tax_divisor) or (item.net_rate) or (item.rate / tax_divisor) %}
+        <PrezzoUnitario>{{ format_float(item_unit_net_price, item_meta.get_field("rate").precision) }}</PrezzoUnitario>
+        {{ render_discount_or_margin(item, tax_divisor) }}
         <PrezzoTotale>{{ format_float(item.net_amount, item_meta.get_field("amount").precision) }}</PrezzoTotale>
         <AliquotaIVA>{{ format_float(item.tax_rate, item_meta.get_field("tax_rate").precision) }}</AliquotaIVA>
         {%- if item.tax_exemption_reason %}